Product Name :
21-Deoxycortisol (CAS 641-77-0)
Synonym :
11β,17α-Dihydroxy-4-pregnene-3,20-dione; 11β,17α-Dihydroxyprogesterone; 21-Desoxycortisol
Application :
CAS:
641-77-0
Purity:
Molecular Weight:
346.46
Formula :
C21H30O4
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
CC(=O)C1(CCC2C1(CC(C3C2CCC4=CC(=O)CCC34C)O)C)O
References:
:Plasma 21-deoxycortisol: comparison of a time-resolved fluoroimmunoassay using a biotinylated tracer with a radioimmunossay using (125)iodine. | Fiet, J., et al. 2000. J Steroid Biochem Mol Biol. 72: 55-60. PMID: 10731638Serum 21-Deoxycortisol, 17-Hydroxyprogesterone, and 11-deoxycortisol in classic congenital adrenal hyperplasia: clinical and hormonal correlations and identification of patients with 11beta-hydroxylase deficiency among a large group with alleged 21-hydroxylase deficiency. | Tonetto-Fernandes, V., et al. 2006. J Clin Endocrinol Metab. 91: 2179-84. PMID: 16551734[21-deoxycortisol. A new marker of virilizing adrenal hyperplasia caused by 21-hydroxylase deficiency]. | Fiet, J., et al. 1989. Presse Med. 18: 1965-9. PMID: 2531882Cell foundry with high product specificity and catalytic activity for 21-deoxycortisol biotransformation. | Xiong, S., et al. 2017. Microb Cell Fact. 16: 105. PMID: 28610588Adrenal C11-oxy C21 steroids contribute to the C11-oxy C19 steroid pool via the backdoor pathway in the biosynthesis and metabolism of 21-deoxycortisol and 21-deoxycortisone. | Barnard, L., et al. 2017. J Steroid Biochem Mol Biol. 174: 86-95. PMID: 28774496A Liquid Chromatography/Tandem Mass Spectometry Profile of 16 Serum Steroids, Including 21-Deoxycortisol and 21-Deoxycorticosterone, for Management of Congenital Adrenal Hyperplasia. | Fiet, J., et al. 2017. J Endocr Soc. 1: 186-201. PMID: 29264476Radioimmunoassay for 21-deoxycortisol: clinical applications. | Gueux, B., et al. 1985. Acta Endocrinol (Copenh). 108: 537-44. PMID: 2986404Congenital Adrenal Hyperplasia: Time to Replace 17OHP with 21-Deoxycortisol. | Miller, WL. 2019. Horm Res Paediatr. 91: 416-420. PMID: 31450227Prenatal diagnosis of 21-hydroxylase deficiency congenital adrenal hyperplasia by simultaneous radioimmunoassay of 21-deoxycortisol and 17-hydroxyprogesterone in amniotic fluid. | Gueux, B., et al. 1988. J Clin Endocrinol Metab. 66: 534-7. PMID: 3258316Reassessment of predictive values of ACTH-stimulated serum 21-deoxycortisol and 17-hydroxyprogesterone to identify CYP21A2 heterozygote carriers and nonclassic subjects. | Costa-Barbosa, FA., et al. 2021. Clin Endocrinol (Oxf). 95: 677-685.NH2-PEG3-C2-Boc Chemical name PMID: 34231242Plasma acyl-carnitines, bilirubin, tyramine and tetrahydro-21-deoxycortisol in Parkinson′s disease and essential tremor.Tributyl(1-ethoxyethenyl)stannane site A case control biomarker study.PMID:33653245 | Albillos, SM., et al. 2021. Parkinsonism Relat Disord. 91: 167-172. PMID: 3464910921-Deoxycortisol is a Key Screening Marker for 21-Hydroxylase Deficiency. | Held, PK., et al. 2022. J Pediatr. 242: 213-219.e1. PMID: 34780778Electroacupuncture May Inhibit Oxidative Stress of Premature Ovarian Failure Mice by Regulating Intestinal Microbiota. | Geng, Z., et al. 2022. Oxid Med Cell Longev. 2022: 4362317. PMID: 36082082Evaluation of 21-deoxycortisol as a marker for the detection of heterozygous carriers of 21-hydroxylase deficiency. | Milewicz, A., et al. 1993. Endokrynol Pol. 44: 187-93. PMID: 8055790The application of a new highly-sensitive radioimmunoassay for plasma 21-deoxycortisol to the detection of steroid-21-hydroxylase deficiency. | Fiet, J., et al. 1994. Ann Clin Biochem. 31 (Pt 1): 56-64. PMID: 8154853