Product Name :
USP36 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
Deubiquitinating enzyme 1 antibody Deubiquitinating enzyme 36 antibody DUB1 antibody FLJ12851 antibody KIAA1453 antibody Ubiquitin carboxyl-terminal hydrolase 36 antibody Ubiquitin specific peptidase 36 antibody Ubiquitin specific processing protease 36 antibody Ubiquitin thioesterase 36 antibody Ubiquitin thiolesterase 36 antibody 展开
Function :
Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin. May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 ‘Lys-4’ trimethylation (H3K4).
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthetic peptide within Human USP36 aa 1,074-1,123 / 1,123.
Species reactivity:
Human
Verify application:
IF-Cell, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
AB_3069039
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 8-Aminoquinoline-3-carboxylic acid Aliquot store at -20℃ or -80℃.3-Carboxypropanesulfonamide Price Avoid repeated freeze / thaw cycles.PMID:33438805
Storage buffer solution:
1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
123 kDa
Positive control :
A549, Hela, LOVO, human liver cancer tissue, human spleen tissue.