Product Name :
Skp1 Recombinant Rabbit Monoclonal Antibody [JM27-37]
Predicted band size :
Observed band size :
Synonyms:
Cyclin A/CDK2 associated p19 antibody Cyclin A/CDK2 associated protein p19 antibody Cyclin-A/CDK2-associated protein p19 antibody EMC19 antibody MGC34403 antibody OCP 2 antibody OCP II antibody OCP II protein antibody OCP-2 antibody OCP-II antibody 展开
Function :
S-phase kinase-associated protein 1 is an enzyme that in humans is encoded by the SKP1 gene. This gene encodes a protein that is a member of the SCF ubiquitin ligase protein complex. It binds to F-box proteins (proteins containing an F-box motif), such as cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin dependent proteolysis. The encoded protein also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors.638217-08-0 site Studies have also characterized the protein as an RNA polymerase II elongation factor.75266-38-5 supplier Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human Skp1 aa 106-155 / 163.
Species reactivity:
Human, Rat, Mouse
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, FC
Coupling :
unconjugated
Clone number:
JM27-37
RRID:
AB_3070570
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33666160 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 19 kDa
Positive control :
PC-12 cell lysates, Hela, SH-SY5Y, human breast tissue.