Product Name :
SMG7 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
breast cancer-associated antigen SGA-56M antibody C1orf16 antibody EST1 like protein C antibody EST1 telomerase component homolog C antibody EST1-like protein C antibody EST1C antibody ever shorter telomeres 1C antibody FLJ23717 antibody hSMG-7 antibody nonsense mediated mRNA decay factor (C. elegans) antibody 展开
Function :
This gene encodes a protein that is essential for nonsense-mediated mRNA decay (NMD); a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex.Mc-Val-Cit-PABC-PNP Chemscene The mRNA decay complex consists, in part, of this protein along with proteins SMG5 and UPF1.Price of 1018446-95-1 The N-terminal domain of this protein is thought to mediate its association with SMG5 or UPF1 while the C-terminal domain interacts with the mRNA decay complex.PMID:33583328 This protein may therefore couple changes in UPF1 phosphorylation state to the degradation of NMD-candidate transcripts. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human SMG7. AA range:521-570
Species reactivity:
Human
Verify application:
WB, IHC-P, IF
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
127 kDa
Positive control :
Bone marrow,Brain,Epithelium,Testis,