Product Name :
PHX2B Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
NBLST2 antibody NBPhox antibody Neuroblastoma paired type homeobox protein antibody Neuroblastoma Phox antibody Paired like homeobox 2b antibody Paired mesoderm homeobox 2b antibody Paired mesoderm homeobox protein 2B antibody Paired-like homeobox 2B antibody PHOX 2B antibody PHOX 2B homeodomain protein antibody 展开
Function :
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome.Formula of 2,4-Dichlorofuro[3,2-d]pyrimidine
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
Synthesized peptide derived from human protein .17288-36-7 Chemscene at AA range: 140-220
Species reactivity:
Human, Mouse
Verify application:
WB
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.PMID:33576127 Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
34 kDa
Positive control :
Brain,Neuroblastoma,